Arthritis: Boron studies show results that no one expected

They have long been looking for simple, economical substances but able to solve important health problems of people, especially the poorer ones, which sometimes gave up to cure themselves for economic problems.
My research has led me to (re)discovery of autohemotherapy that manages to cure about 100 pathologies with a simple injection of your blood, the iodine Lugol, also this super economic that manages the same to cure and solve problems such as hormonal problems, cited in the various organs, cysts and nodules to the breast, ovaio policistico, prostate and much more.
My last discovery I reported in my last published book is the boro.
A simple substance, easily available, which allows with an expense under 20 euros to be able to cure different pathologies for several months!
In this article we will talk about the boro for the care of arthritis, a very common pathology in Italy.

In recent years this substance has attracted more and more attention in the world of research for the possible role of support in the health of bones and joints. When we talk about arthritis, in fact, we tend to focus only on anti-inflammatory drugs (and their side effects always present!) or on the most known therapies, but there are also micronutrients that seem to significantly affect the inflammatory and degenerative processes of the organism. Among these, the boron is one of the most interesting elements.
Arthritis, both in the osteoarthritis and rheumatoid form, is a condition that affects millions of people and which can deeply affect the quality of life. Pain, joint stiffness, chronic inflammation and difficulty in movements often become daily companions. In this context, studies have observed that people with a higher supply of boron tend to have a lower incidence of joint disorders than populations taking very low amounts.

The boron is a naturally present oligo element especially in plant foods such as fruit, vegetables, avocado, almonds, dried plums and raisins. Although it is not yet considered "essential" according to all official nutritional criteria, numerous research suggests that it participates in several important biological processes. One of its main roles is the metabolism of calcium, magnesium and vitamin D, fundamental elements to maintain strong bones and healthy joints. But what most affected the researchers is its possible anti-inflammatory action. Some studies have shown that boron can affect certain cell mechanisms involved in chronic inflammation, helping to reduce the production of pro-inflammatory substances such as TNF-alpha, interleukins and C-reactive protein. In practice, it would seem to help the organism to "spegnere" part of that persistent inflammation that characterizes many joint diseases.

A particularly interesting fact is that in several patients suffering from osteoarthritis and rheumatoid arthritis, lower levels of boron in the blood, bones and even in the synovial fluid than healthy subjects were detected. This does not automatically mean that boron deficiency is the cause of the disease, but it still suggests a possible connection between low levels of this mineral and worsening of joint degenerative processes. Epidemiological observations showed curious results. In some areas of the world where daily boron intake is very low, the incidence of arthritis appears much higher. On the contrary, in populations that naturally introduce more bore through food, cases seem to be much lower.

Animal studies have also provided encouraging results. In experimental arthritis models, boron administration showed a reduction in joint inflammation and an improvement of different parameters related to joint damage. This has strengthened the hypothesis that the boron can play an active role in the modulation of the inflammatory response. Clinical research on man is still limited, but some have highlighted particularly interesting results. One of the most mentioned studies is the double-blind pilot published in 1990 by Travers and collaborators. In this research, 20 patients with osteoarthritis received 6 mg per day of boron in the form of sodium tetraborate or placebo for 8 weeks. The results showed that 50% of the subjects treated with boron reported an improvement of symptoms, compared to just 10% of the placebo group. Even more interesting is the fact that, among patients who completed the study, 71% of the boron group declared significant benefits, without particular side effects.

Other studies have analysed the so-called fructoborate calcium, a form of boron present naturally also in some plants and fruits. In patients with mild or moderate osteoarthritis, dosages between 6 and 12 mg daily showed pain reductions, joint stiffness and even anti-inflammatory drugs. In several cases an improvement in mobility and joint flexibility has been observed. Some trials also highlighted an important reduction of inflammatory markers such as C-reactive protein and phybrinogen. Also in rheumatoid arthritis are evidenced preliminary noteworthy. A pilot study evaluated boron as an additional support for etanercept, a biological drug used in the most important inflammatory forms. Patients taking 6 mg per day of boron, especially in the form of fructoborate calcium, showed improvements in clinical scores and a reduction of TNF-alpha and other inflammatory cytokines. In this study the fructoborate calcium seemed to offer better results than the simple borace.

Other short-term research, with dosages between 1.5 and 6 mg per day, also reported a reduction in knee pain and inflammatory markers in subjects with osteoarthritis. Overall, the benefits observed seem to concern especially pain, joint stiffness and general inflammation. It should however be pointed out that many of these studies have been conducted on small groups of people and not always with perfect methods.

The possible mechanisms through which the boron could act are multiple. In addition to the reduction of NF-κB activation and inflammatory cytokines, it seems to contribute to cartilage health, support collagen metabolism and promote better bone mineral density. Some researchers also suggest a positive interaction with steroid hormones and vitamin D, both essential for osteoarticular well-being. To this are added possible antioxidant properties that could help limit cell damage associated with chronic inflammation.

From the safety point of view, boron is generally well tolerated in doses used in most clinical studies, usually between 3 and 10 mg per day. However, there are populations taking much higher quantities without apparent negative effects. In some areas of the world, such as Israel, where natural waters are particularly rich in boron, daily intake can also reach about 75 mg per day through drinking water, without particular health problems being observed. This suggests that boron tolerance could be wider than you often think.
È importante evidenziare che il boro non rappresenta una cura miracolosa per l’artrite e non deve sostituire i trattamenti prescritti dal medico. Tuttavia, i dati disponibili suggeriscono che potrebbe rappresentare un valido aiuto per chi ha problemi di artrite all’interno di un approccio più ampio che comprenda alimentazione corretta, attività fisica, controllo dell’infiammazione e stile di vita sano.

Studi principali citati:

Newnham RE. Essentiality of boron for healthy bones and joints. Environmental Health Perspectives, 1994.

Travers RL et al. Boron and arthritis: the results of a double-blind pilot study. Journal of Nutritional Medicine, 1990.

Nielsen FH. Growing Evidence for Human Health Benefits of Boron. Journal of Evidence-Based Complementary & Alternative Medicine, 2011.

Scorei R et al. Studi sul calcio fructoborato e salute articolare.

Li G et al. The Impact of Trace Elements on Osteoarthritis. Frontiers in Medicine, 2021.

Hussain SA et al. Studio sull’utilizzo del boro come supporto nell’artrite reumatoide associato a etanercept.

Office of Dietary Supplements (NIH). Boron Fact Sheet, aggiornamento 2022.